Atsetylsalytsylovaya acid [ Magnesium hydroxide] | Cardiomagnyl tablets 150 mg + 30.39 mg 30 pcs.

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BID480984
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Pharmacological action

Antiplatelet.

Acetylsalicylic acid irreversibly inhibits the cyclooxygenase enzyme and selectively reduces the synthesis of thromboxane A2, which leads to a decrease in platelet aggregation and a decrease in blood coagulability.

Magnesium hydroxide protects the gastrointestinal mucosa, which reduces the risk of side effects.
Pharmacological action

Antiplatelet.

Acetylsalicylic acid irreversibly inhibits the cyclooxygenase enzyme and selectively reduces the synthesis of thromboxane A2, which leads to a decrease in platelet aggregation and a decrease in blood coagulability.

Magnesium hydroxide protects the gastrointestinal mucosa, which reduces the risk of side effects.

Indications

prophylaxis of thrombosis and embolism

prophylaxis of myocardial infarction (including with unstable angina)

prophylaxis of cerebrovascular accidents by ischemic type

transient transient cerebral ischemic heart disease (srd) and hours after coronary artery bypass grafting and percutaneous transluminal coronary angioplasty).

Contraindications

bleeding in the gastrointestinal tract history

cerebrovascular for hemorrhagic type history

thrombocytopenia

hemophilia

hemorrhagic diathesis

bleeding tendency

hypoprothrombinemia

asthma

deficiency of glucose-6-phosphate dehydrogenase

renal failure

I and III trimester

lactation (breastfeeding)

children and adolescents under 18

hypersensitivity to acetylsalicylic acid or salicylate am

Pregnancy and lactation The drug is contraindicated for use in the I and III trimesters of pregnancy and during lactation (breastfeeding).

Use during pregnancy and lactation

The use of high doses of salicylates in the first trimester of pregnancy is associated with an increased incidence of fetal developmental defects. In the second trimester of pregnancy, salicylates can only be prescribed with a strict assessment of risk and benefit. In the III trimester of pregnancy, salicylates in a high dose (more than 300 mg / day) cause inhibition of labor, premature closure of the ductus arteriosus in the fetus, increased bleeding in the mother and fetus, and administration immediately before birth can cause intracranial hemorrhage, especially in premature babies. The appointment of salicylates in the I and III trimesters of pregnancy is contraindicated.

Salicylates and their metabolites are excreted in small amounts with breast milk. A random intake of salicylates during lactation is not accompanied by the development of adverse reactions in the child and does not require cessation of breastfeeding. However, with prolonged use of the drug or the appointment of a high dose, breast-feeding should be stopped immediately.

Special instructions

With caution, prescribe the drug in patients with a history of gastric ulcer.

The patient should be warned about the need to consult a doctor if any adverse events occur.

Composition

Tablets, film-coated, white, oval, with a risk on one side.

Active Ingredients

Acetylsalicylic acid 150 mg in 1 tablet.

Magnesium hydroxide 30.39 mg in 1 tablet.

Excipients

Corn starch.

Microcrystalline cellulose.

Magnesium stearate.

Potato starch.

Hypromellose (methylhydroxypropyl cellulose 15).

Macrogol (propylene glycol).

Talc.

Dosage and administration

Tablets should be swallowed whole with water. If desired, the tablet can be broken in half, chewed or pre-ground.

Primary prophylaxis of cardiovascular diseases For the primary prophylaxis of cardiovascular diseases such as thrombosis and acute heart failure in the presence of risk factors (e.g. diabetes mellitus, hyperlipidemia, hypertension, obesity, smoking, old age), 1 tab. Cardiomagnyl containing acetisalicylic acid in a dose of 150 mg on the first day, then 1 tab. Cardiomagnyl containing acetisalicylic acid in a dose of 75 mg 1 time / day.

Prevention of repeated myocardial infarction and blood vessel thrombosis. For the prevention of repeated myocardial infarction and blood vessel thrombosis, 1 tab. Cardiomagnyl containing acetisalicylic acid in a dose of 75-150 mg 1 time / day.

Prevention of thromboembolism after vascular surgery For the prevention of thromboembolism after vascular surgery (coronary artery bypass grafting, percutaneous transluminal coronary angioplasty), 1 tab. Cardiomagnyl containing acetisalicylic acid in a dose of 75-150 mg 1 time / day.

With unstable angina, 1 tab. Cardiomagnyl containing acetisalicylic acid in a dose of 75-150 mg 1 time / day.

Overdose of

For adults, a dose of the drug corresponding to 150 mg of acetylsalicylic acid per 1 kg of body weight is dangerous.

Symptoms: tinnitus, hearing loss, dizziness, increased sweating, anxiety, abdominal pain, nausea, vomiting (possibly with blood), increased breathing, increased bleeding rarely - impaired heart function in rare cases - pulmonary edema.

Treatment: symptomatic therapy is given if necessary.

Storage conditions

In a place protected from light and moisture at a temperature of 15-30 РC.

Keep out of the reach of children.

Pharmacy terms

Without a prescription

lekarstvennaja form

tablets

Prescription

Pregnant as prescribed by the doctor, Nursing mothers as prescribed by the doctor, Adults doctor's prescription

Indications

From angina, From heart failure, Prevention of heart attacks and strokes, Prevention of thrombosis

Takeda GmbH, Japan

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